One crisis after another always has an impact on tourism and the hospitality industry. Whether it is the war in Ukraine, the aftermath of the covid pandemic, the economic consequences, primarily the increase in inflation, the adaptations linked to sustainable development, not to mention other effects, create complex jolts and uncertainties. The 2022 edition of the MITF will allow, as in previous editions, to develop the indispensable reflections and exchanges of good practices to face and respond to all these challenges, new or renewed. In parallel with these elements, it is also a question of acting at the local and regional level. In the French-speaking region, this implies cross-border thinking, as the people who visit our areas do not intend to limit themselves to borders. At the MITF 2022, a module is devoted to possible cross-border cooperation in tourism. There is no doubt that, in this situation of transitions and structural and economic changes, those responsible for the various tourism and hospitality sectors must get together and discuss possible developments and future changes to the known models.